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  1. http://www.medpagetoday.com/Endocrinology/Obesity/50500 http://www.nature.com/srep/2015/150309/srep08889/full/srep08889.html#close It's beginning to look like the initial hype was based on misinterpreted results. Shit, did I say "beginning"? There was some indication of this a couple of years ago: https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0033-1336630 Question is: Despite the fact that humans don't seem to produce functional Irisin, would it serve any role in humans? That is to say: Would exogenous administration prove beneficial?