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Fish oil and female sexuality

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I was directed to this board by a helpful acquaintance. I am working with some doctors at the NIH and Columbia University and we are about to begin a double-blind, placebo-controlled study of high-dose fish oil on female sexuality. My friend told me there were lots of women here who were already taking high-dose fish oil (more than a gram and a half of EPA and over a gram of DHA per day) who had not noticed an improvement in libido, or at least had made no mention of improvement in libido. I'd like to check with them before the study begins, if that's all right. Don't want to waste a lot of money.

 

-Marrena Lindberg

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I hope you decide to follow through with this.

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Hmm........I have used up to a total of 6G of EPA/DHA per day and have never noticed any changes in libido. Then again, I don't have too many libido issues to be worried about. :ph34r:

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Aren't you really asking about dosing of DHA, EPA and ovarian steroidogenesis. In other words, DHA testosterone production in women, with respect to libido?

 

There was a very interesting little article, back in 2004, that suggested a reconversion mechanism at play in postmenopausal women fed high dose DHA (2.6g), tow groups, one on HRT and the other not receing HRT treatment.

 

http://www.ajcn.org/cgi/content/full/79/5/765

 

And this paper indicates a nice relationship between liver lipids and DHA administration:

 

http://www.jacn.org/cgi/content/abstract/24/3/189

 

And if you look to the literature on hyperandrogenemia in women, you'll find a very nice connection between elevated DHEA-S and decreased triglycerides.

 

In other words, liver lipid metabolism might be altered by DHA, which could boost lipid supressed (FXR gene receptor regulation) adrenal production of testosterone and the precustors for additional testosterone production in thecal and peripheral tissue.

 

And we haven't even touched on DHA effects in brain, have we?

 

You find three populations here. Those who have stress and diet altered liver lipid biosynthesis, with feedback reprression of thyroid and adnreal steroidiogenesis.

 

And you will also find a group of normally regulated (with respect to liver lipid and hormone rgulation) individuals who will exhibit a mild response to DHA, with an increase in testosterone (assuming that critical testosterone binding muscle mass condition is met, and dietary control of SHBG is present).

 

The third group are the hyperandrogenic folks who may have a differential response to DHA administration. They may have altered AA synthesis or sensitivity, and thus down regulation of elevated testosterone production at high doses of PUFA-3, while exhibiting a slight boost or no additional elevation of testosterone at lower doses.

 

Estrogen production will be an important factor, as it will vary with respect to age and liver lipid biosynthetical pathway regulation aterations.

 

The key: insulin regulation and its role in glucose and fatty acid metabolic regulation. Look to that factor for coutner regulation of fatty acid metabolism (which has been shown to be boosted by DHA and EPA administration).

 

Long chain fatty and certain lipophylic phytosterols are all important for their synergetic effect on correcting impaired liver function, eh?

 

You will find us to be are an interesting rat population.

 

Like Jodi, I enjoy mildly elevated production of testosterone. No problems with libido, when my insulin production is controlled.

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Wow. I've been looking all over the place for EPA and DHA hormonal influences and couldn't find it. You are incredibly well-informed.

 

I am more weighted on the female sexuality side of things. Free testosterone is only one of four things that influences female sexuality, the others are being high dopamine relative to serotonin, good genital blood circulation and strong PC muscle tone. Of course fish oil elevates dopamine and improves circulation, including nitric oxide a la Viagra, and I thought it was just that, although I have long suspected a hormonal connection.

 

Some women on my diet with good PC muscle tone and low SHBG develop spontaneous vaginal orgasm ability and very, very high libido.

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Some women on my diet with good PC muscle tone and low SHBG develop spontaneous vaginal orgasm ability and very, very high libido.

 

ActivaTe for the ladies then?

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ActivaTe for the ladies then?

 

What's that?

 

Okay, found it. I prefer that women eat 40/30/30 with carbs mainly from fruits and vegetables and also take the RDA of calcium/magnesium/zinc to keep SHBG down. And I also recommend avoiding hormonal birth control. It's hard enough to get women to try my diet with just fish oil and vitamins and minerals.

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ActivaTe is a proprietary extract of Urtica dioica produced by Designer Supplements and standardized to a high fraction of the constiuent that lowers SHBG. Its non-steroidal so should be okay for women to take and, I suspect, if they started having more orgasms as a result, they would keep on taking it. ;)

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Wait, trouble is saying that high-dose fish oil will cause problems with insulin? That contradicts studies that show that fish oil improves diabetes.

 

Unlike men, women are far less motivated to take things to improve sexual function. Even the fish oil is a very difficult sell.

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Unlike men, women are far less motivated to take things to improve sexual function.

 

That is so sad...

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A true tragedy.

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Wait, trouble is saying that high-dose fish oil will cause problems with insulin? That contradicts studies that show that fish oil improves diabetes.

 

Unlike men, women are far less motivated to take things to improve sexual function. Even the fish oil is a very difficult sell.

 

Bullshit. Inability or extreme difficulty at achieving orgasm is the number one sexual complaint among women.

 

Libido itself is a different story. Many women, speaking only from my experience speaking with / listening to them, attribute a lot of their bad relationship behaviors to being blinded by libido. To paraphrase from a William Gibson novel: "'Men have it easy,' she thought to herself. 'When there is something wrong with their partner they can't even get hard, whereas a woman can think at one moment that everything in the world is wrong with their partner and then still jump right into bed with him after he flashes a smile.'" I'm Pure conjecture, but I guess that is probably the big issue with trying to market a libido enhancer to women. If women were so cold on sexual sensation enhancement then I wouldn't have had to fight every girlfriend I've ever had about using condoms, their best judgments about practicality notwithstanding.

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Bullshit. Inability or extreme difficulty at achieving orgasm is the number one sexual complaint among women.

 

I think you are missing my point. Sexual problems of any kind, whether pertaining to libido or orgasmic ability, are generally considered much lower in importance by women than by men. These are generalities, of course there are exceptions.

 

I am not here to argue or prove a point. Frankly I'm tired of arguing. I just want to hear about the experiences of women who are taking at least a gram of DHA a day and have healthy hormone levels and are able to menstruate, and who aren't on antidepressants. In particular, in remembering back to before they started taking the fish oil, have they seen an improvement in libido and/or orgasmic ability.

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I am more weighted on the female sexuality side of things. Free testosterone is only one of four things that influences female sexuality, the others are being high dopamine relative to serotonin, good genital blood circulation and strong PC muscle tone. Of course fish oil elevates dopamine and improves circulation, including nitric oxide a la Viagra, and I thought it was just that, although I have long suspected a hormonal connection.

 

Some women on my diet with good PC muscle tone and low SHBG develop spontaneous vaginal orgasm ability and very, very high libido.

"I find your ideas intriguing and wish to subscribe to your newsletter."

 

Can you say more about blood circ and PC (pelvic?) muscle tone?

 

And do you know anything cool about the female orgasm? Is the 'floating' sensation due to the cerebellum's involvement?

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Any new research on fish oil and testosterone? Just curious. My book is already published and all--I just got a question on my messageboard and I was curious. I certainly receive a lot of feedback from people just taking high dose fish oil that their hair and skin become oilier, so I'm pretty sure this correlation exists, but I can't find anything new in the literature. Maybe it's not being studied?

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